Status:

TERMINATED

Intermittent Oral-esophageal Tube Feeding in Delayed Dysphagia After Radiotherapy for Nasopharyngeal Carcinoma

Lead Sponsor:

Zeng Changhao

Conditions:

Nasopharyngeal Carcinoma

Dysphagia

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy for NPC. Patients enrolled are randomly divided equally into the observation group and the control group...

Detailed Description

Palliation to delayed dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC) continues to be a challenge. Although nasogastric tube feeding (NGT) has been adopted widely, the weaknesses have ...

Eligibility Criteria

Inclusion

  • Age between 18 and 65 years.
  • With the history of NPC and radiation therapy.
  • With dysphagia occurred at least three years after radiotherapy (confirmed by videofluoroscopic swallowing study), in need of and feasible for enteral nutrition support.
  • Conscious and with stable vital signs;
  • Willing to participate and sign the written informed consent form either personally or by a family member.

Exclusion

  • Presence of other diseases that might cause dysphagia.
  • With distant metastasis of tumors, or complicated with severe systemic disorders or malignancies.
  • Concurrent participation in other treatments that could interfere with the trial.
  • Inability to cooperate with treatment due to aphasia, mental health issues, etc.
  • Received tube feeding for enteral nutrition support within the past three years.

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT06189482

Start Date

June 1 2022

End Date

December 31 2022

Last Update

March 12 2024

Active Locations (1)

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1

Zheng da yi fu yuan hospital

Zhengzhou, Henan, China, 450000