Status:
COMPLETED
Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers
Lead Sponsor:
I.M. Sechenov First Moscow State Medical University
Conditions:
Healthy Volunteers
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Observational, randomized studies and their meta-analyses have shown the high effectiveness of high-flow oxygen therapy through nasal cannulas, reaching 50-60% in acute hypoxemic respiratory failure. ...
Detailed Description
Randomized controlled trials showed reduction of tracheal intubation in high-flow oxygen therapy through nasal cannulas group in patients with acute respiratory failure as compared to standard oxygen ...
Eligibility Criteria
Inclusion
- Healthy Volunteers
- Age over 18 years
- Written informed consent.
Exclusion
- Any primary or secondary lung diseases (COPD, bronchial asthma, interstitial lung diseases, metastatic lung disease, lung cancer)
- Any chronic diseases that can cause respiratory disorders (chronic heart failure, liver cirrhosis, systemic connective tissue diseases, cancer, neuromuscular diseases etc)
- Heart rhythm disturbances
- Body mass index more than 30 kg/m2
- Swallowing disorders
- History of epileptic syndrome
- Recent head surgery or anatomy that precludes the use of nasal cannulas
- Pregnancy and lactation period
- Inability to cooperate with staff.
Key Trial Info
Start Date :
January 9 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 10 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06189716
Start Date
January 9 2024
End Date
June 10 2024
Last Update
October 8 2024
Active Locations (1)
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1
Sechenov University Clinic#4
Moscow, Moscow, Russia