Status:

RECRUITING

Role of the Fibroblast Activation Protein (FAP) as Biomarker of Fibrotic Lung Diseases

Lead Sponsor:

Erasme University Hospital

Conditions:

Pulmonary Fibrosis

Lung Fibrosis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

To evaluate the effect of an anti-fibrotic treatment initiation on the fibrotic activity as assessed by FAPI PET/CT.

Detailed Description

To evaluate the use of the fibroblast activation protein (FAP) as a biomarker of fibrotic lung disease (idiopathic pulmonary fibrosis (IPF) and non-IPF ILDs). The study will include both analysis of F...

Eligibility Criteria

Inclusion

  • Adults patients with a fibrotic lung disease (idiopathic pulmonary fibrosis (IPF) or non-IPF fibrotic ILD) as defined according to the 2022 ATS/ERS/JRS/ALAT Clinical Practice Guidelines

Exclusion

  • Pregnant or nursing patients
  • Patients with another significant medical condition which, in the investigator's opinion, may interfere with the completion of the study.
  • Patients with an active lung neoplasm or any active neoplasm for blood samples

Key Trial Info

Start Date :

March 9 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 9 2027

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06189820

Start Date

March 9 2023

End Date

March 9 2027

Last Update

January 5 2024

Active Locations (1)

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Medecine

Brussels, Belgium, 1070