Status:
ACTIVE_NOT_RECRUITING
Impact of Advanced Platelet Rich Fibrin and Enamel Matrix Derivative on Clinical and Molecular Wound Healing Parameters After Surgical Removal of Mandibular Third Molars
Lead Sponsor:
University of Belgrade
Conditions:
Surgical Wound, Healed
Post Operative Pain
Eligibility:
All Genders
18-30 years
Phase:
PHASE4
Brief Summary
Brief summary The goal of this study is to compare the effects of advanced platelet rich fibrin and enamel matrix derivative placed in the extraction alveoli of patients who had surgical removal of m...
Detailed Description
Surgical removal of impacted mandibular wisdom teeth is often related to the occurrence of postoperative pain, swelling, trismus and sometimes to the development of complications such as alveolar oste...
Eligibility Criteria
Inclusion
- Systemically healthy individuals (ASA I by American Society of Anesthesiologists classification);
- Age 18-30 years;
- Patients who have bilaterally impacted mandibular wisdom teeth which are in contact with the distal surface of the second mandibular molar.
Exclusion
- Systemic disorders;
- Patients who have difficulties when phlebotomy is performed
- History of pericoronitis in the area of impacted mandibular wisdom tooth
- History of NSAIDs, corticosteroids and antibiotics intake within 10 days before surgery
Key Trial Info
Start Date :
May 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 20 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06190015
Start Date
May 23 2022
End Date
March 20 2024
Last Update
January 5 2024
Active Locations (1)
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1
School of dental medicine, University of Belgrade
Belgrade, Serbia, 11000