Status:

RECRUITING

Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Conditions:

Congenital Heart Disease

Neurodevelopmental Disorders

Eligibility:

All Genders

Up to 6 years

Brief Summary

Infants with congenital heart disease (CHD) are at increased risk for delayed neurodevelopment. Multiple etiological explanations have been proposed, as there seems to be a multifactorial interplay of...

Eligibility Criteria

Inclusion

  • CHD warranting a first percutaneous or surgical intervention in the first 6 months, including but not limited to transposition of the great arteries (TGA), univentricular heart (UVH), Tetralogy of Fallot (TOF), coarctation of the aorta (CoA), total abnormal pulmonary venous drainage (TAPVU), Common arterial trunc (TA), large patent ductus arteriosus (PDA) or VSD and AVSD for which treatment is necessary within the first 6 months of life.
  • Treatment provided at the University Hospitals Leuven.

Exclusion

  • Syndromes or proven genetic conditions which are associated with neurological impairment
  • CHD warranting treatment after 6 months of life
  • Suspected or proven metabolic diseases
  • No parental/guardian consent

Key Trial Info

Start Date :

December 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2027

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06190210

Start Date

December 1 2023

End Date

September 30 2027

Last Update

April 2 2025

Active Locations (1)

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UZ Leuven

Leuven, Vlaams-Brabant, Belgium, 3000