Status:
COMPLETED
Effect of a Global Simplified Strategy on Thromboembolic Events in Emergency Department Patients with Suspected Pulmonary Embolism
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Pulmonary embolism (PE) is frequently suspected in emergency departments (ED) patients which often leads to the prescription of DDimer testing and irradiative chest imaging (Computed Tomographic Pulmo...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- ED adult patients with suspected pulmonary embolism defined as:
- New onset of or worsening shortness of breath
- Or Chest pain
- Or Syncope in the absence of any obvious other cause (such as pneumothorax, asthma attack, ST elevation myocardial infarction, trauma, etc.)
- Patient able to understand and give oral consent
- Informing and obtaining the patient's oral consent
- Social security affiliation (except AME)
Exclusion
- Patients currently treated with full-dose anticoagulant therapy
- Diagnosed thrombo-embolic event in the past 6 months
- PE ruled out by the PERC rule (low clinical probability and none of the 8 items of the PERC score)
- Acute severe presentation (clinical signs of respiratory distress, hypotension, SpO2 \< 90%, shock)
- DDimer level known before ED visit
- Patient living in assisted-living home or nursing home or palliative center. Anticipated life expectancy \< 3 months or "do not resuscitate" order
- Patient under legal protection measure (tutorship or curatorship) and patient deprived of freedom
- Pregnancy and breastfeeding
- Participation in another interventional trial
Key Trial Info
Start Date :
January 19 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 21 2025
Estimated Enrollment :
1223 Patients enrolled
Trial Details
Trial ID
NCT06190392
Start Date
January 19 2024
End Date
January 21 2025
Last Update
February 7 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Emergency department Hospital Pitié-Salpêtrière
Paris, France, 75013