Status:
RECRUITING
Impact of Gravity on Cardiac Hemodynamics
Lead Sponsor:
University Hospital, Caen
Collaborating Sponsors:
INSERM UMR-S 1075 COMETE, Caen, France
CNRS UMR 5220 INSERM U1294 CREATIS ,Université Lyon 1, INSA Lyon, France
Conditions:
Diabetes type1
Healthy
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to define and compare pre-load dependance of the cardiac function according to the intracardiac hydrostatic gradient of pressure in healthy and diabetic populations....
Detailed Description
Gravitational force affects both the cardiac mass and the thoracic compartment. However, few studies in humans have explored whether the relationship between cardiac function and load-dependence varie...
Eligibility Criteria
Inclusion
- Affiliated to the social security system
- Patient informed of the study and having signed an informed consent form
- Type 1 diabetes for at least 10 years followed at Caen University Hospital, equipped with a continous glucose monitoring system
Exclusion
- Trained athletes (≥ 6 hours of sustained physical exercise \>70% VO2max per week for \> 6 months)
- Chronic cardiovascular disease or cardiovascular treatment
- Personal history of chemotherapy and/or thoracic radiotherapy
- Cerebral and/or spinal disease
- Inclusion of the subject in another biomedical research protocol of interventional type (during the study or in the 3 months prior to inclusion)
- Pregnant, breast-feeding or parturient women
- Adults under legal protection (guardianship, curators) or unable to express their consent or deprived of their freedom
Key Trial Info
Start Date :
November 22 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 15 2025
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT06190756
Start Date
November 22 2023
End Date
October 15 2025
Last Update
March 26 2025
Active Locations (1)
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1
Inserm 1075 Comete, Unicaen
Caen, France, 14000