Status:
COMPLETED
Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
Lead Sponsor:
Kessler Foundation
Collaborating Sponsors:
Consortium of Multiple Sclerosis Centers
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
Detailed Description
The purpose of this research study is to learn how different types of cycling exercise can improve short-term processing speed, or speed of thinking, in persons with MS. In this study, we will compare...
Eligibility Criteria
Inclusion
- Speak English as their primary language
- Confirmed MS diagnosis by a neurologist
- Be relapse and steroid-free for at least 30 days
- Mild-to-moderate self-report mobility disability
Exclusion
- History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression)
- Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q)
- Currently use medications that may impact cognition (ex: steroids, benzodiazepines)
- Currently pregnant
- Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M)
- No indication of age-related mild cognitive impairment or dementia, based on the MOCA-Blind (i.e., MOCA-Blind ≥19).
- High likelihood of motion sickness
- Regular cyclist, defined as cycling for at least 150 minutes/week
Key Trial Info
Start Date :
February 12 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 28 2025
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT06191380
Start Date
February 12 2024
End Date
October 28 2025
Last Update
October 30 2025
Active Locations (1)
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1
Kessler Foundation
East Hanover, New Jersey, United States, 07936