Status:
RECRUITING
Risk and Resilience to Suicide Following Late-Life Spousal Bereavement
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Suicide
Bereavement
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
The purpose of the RISE study is to examine how the 24-hour rhythm of sleep and social activity relate to mood and suicidal ideation among older adults that recently lost a spouse or life partner.
Detailed Description
Experiencing the death of a spouse or life partner is a profoundly distressing event that may cause abrupt changes in one's daily routine, including decreased self-care and withdrawal from social acti...
Eligibility Criteria
Inclusion
- Older adults who recently lost their spouse or life partner and are high risk for suicidal thoughts and/or behavior.
- Bereaved \< or = to 12 months from spousal/partner loss
- \> or = to 65 years old
- Verified history of suicide attempt/attempts and/or current or past history of Major Depressive Disorder/Major Depressive Episode (MDD/MDE) (without psychotic features), or history of depression severe enough to trigger treatment, or current subsyndromal depression (\> or = to 9 HDRS)
- No diagnosis of schizophrenia/schizoaffective disorders/bipolar/current psychosis
- Does not reside in nursing home
- Not a current shift worker
- No major cognitive impairment: TICS score of \> or = to 27
Exclusion
- Bereaved \>12 months from spousal/partner bereavement
- \< 65 years old
- Patient is not spousal/partner bereaved (ex: parent, sibling, etc.)
- Prior diagnosis of schizophrenia/schizoaffective disorders/bipolar/current psychosis or medications listed indicate diagnosis of these disorders/MDD or MDE with psychotic features
- Major cognitive impairment: TICS score of \<27
- Current shift worker
- Resides in a nursing home
- Unstable medical condition (e.g., unstable angina, end stage renal disease)
Key Trial Info
Start Date :
November 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2029
Estimated Enrollment :
169 Patients enrolled
Trial Details
Trial ID
NCT06191484
Start Date
November 20 2023
End Date
December 1 2029
Last Update
November 12 2025
Active Locations (1)
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1
University of Pittsburgh (UPMC)
Pittsburgh, Pennsylvania, United States, 15212