Status:
ACTIVE_NOT_RECRUITING
Effects of an Acceptance-based Medication Adherence Therapy for Recent-onset Psychosis
Lead Sponsor:
Chinese University of Hong Kong
Collaborating Sponsors:
Integrated Community Centers for Mental Wellness
Conditions:
Early Psychosis
Psychotic Disorders
Eligibility:
All Genders
18-64 years
Phase:
NA
Brief Summary
This randomized controlled trial aimed to examine the effectiveness of a 10-session acceptance-based, insight-inducing medication adherence therapy (AIM-AT) program for recent-onset psychosis (in addi...
Detailed Description
Objectives: To evaluate the effectiveness of an Acceptance-based, Insight-inducing Medication Adherence Therapy (AIM\_ AT) for recent-onset psychosis on patient outcomes over 12-month follow-up, when ...
Eligibility Criteria
Inclusion
- primarily diagnosed with psychosis (termed recent-onset), including brief, first-episode and other psychotic disorders according to the criteria of the DSM-V (American Psychiatric Association, 2013);
- had the mental illness ≤5 years (defined as recent-onset psychosis in recent literature)
- Hong Kong Chinese residents, aged 18-64 years;
- Global Assessment of Functioning scores ≥51, indicating mild to moderate symptoms and difficulties in psychosocial/occupational functioning (American Psychiatric Association, 2013), thus being mentally stable to comprehend AIM\_AT and/or psychoeducation training;
- Unsatisfactory medication adherence as indicated by the Adherence Rating Scale of \<2 (Hayward et al.,1995) during screening; and
- Able to read/understand Cantonese/Mandarin.
Exclusion
- Participated in/have recently been receiving other psychotherapies;
- Having comorbidity of another mental illness (learning disability, cognitive or personality disorder) and/or clinically significant medical disease; and
- Having communication and/or visual/hearing difficulty.
Key Trial Info
Start Date :
February 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2025
Estimated Enrollment :
126 Patients enrolled
Trial Details
Trial ID
NCT06192602
Start Date
February 1 2023
End Date
December 31 2025
Last Update
August 26 2025
Active Locations (1)
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1
Integrated Community Centers for Mental Wellness
Hong Kong, New Territories, Hong Kong