Status:
UNKNOWN
Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
Lead Sponsor:
Xiaoyong Zeng
Conditions:
Urethral Stricture, Male
Eligibility:
MALE
18+ years
Phase:
NA
Brief Summary
The field of research for this study is tissue engineering and the utilization of a small intestinal submucosa graft as a substitute biomaterial for conventional buccal mucosa in substitution urethrop...
Detailed Description
Urethral stricture refers to the abnormal narrowing of the urethral lumen resulting from fibrosis that affects the urethral epithelium and underlying corpus spongiosum. The management of urethral stri...
Eligibility Criteria
Inclusion
- Patients signed informed consent form
- Patients with a single, longer than 2.0 cm and shorter than or equal to 7.0 cm anterior urethral stricture
- Patients undergoing substitution urethroplasty for urethral stricture.
Exclusion
- Patients without surgical indication
- Subtotal and total urethral strictures
- Radiation therapy to the abdomen or pelvis
- Lichen sclerosis related strictures
- Patients with previous hypospadias repair
- Neurogenic urinary tract disorders
- Mental disorders
- Patients with a known biologic sensitivity or a cultural aversion to the use of porcine materials.
- Patients with severe dysfunction of heart, lung, liver, kidney and other important organs , endocrine system and blood system.
- Patient with malignant tumor
- Patient who cannot be regularly examined due to any circumstances
- Any clinical state which does not ensure the safe implementation of study procedure (investigator's view)
Key Trial Info
Start Date :
November 10 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06192654
Start Date
November 10 2023
End Date
December 30 2025
Last Update
January 5 2024
Active Locations (1)
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1
Tongji hospital
Wuhan, Hubei, China