Status:

COMPLETED

Impact of a Probiotic-based Formula on Digestive Symptoms and Mood in Ultra Marathon Runners

Lead Sponsor:

AB Biotics, SA

Conditions:

Signs and Symptoms

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Randomized, prospective, double-blind, placebo-controlled study in ultramarathon runners to evaluate the effects of suplementation with i3.1 probiotic formulation on the relief of common digestive sym...

Detailed Description

Gastrointestinal symptoms (GIS) are a common feature of intense exercise, especially in ultra-endurance events. The main objective of this study is to evaluate the impact of a 3-strain probiotic formu...

Eligibility Criteria

Inclusion

  • Age \>18 years
  • Correctly registered in the Salomon Ultra Pirineu 100K® 2023 race
  • Stable medication planned during the study period
  • Willing to provide informed consent and follow study procedures
  • Have signed the consent provided by the organization of the Salomon Ultra Pirineu 100K® 2023 race

Exclusion

  • Respiratory, gastrointestinal or systemic infection that has caused fever or fatigue in the 15 days prior to the study entry
  • Having taken probiotic-based supplements or dairy products with probiotics (including "Actimel" or yogurts with "bifidus") daily in the 15 days prior to the study start
  • Taking oral or parenteral antibiotics in the 15 days prior to the study start
  • History of gastrointestinal surgery within 6 months prior to the study start
  • History of cardiovascular event: angina, heart failure, myocardial infarction
  • Diabetes mellitus type 1 or 2
  • Pregnancy or lactation, or women planning to conceive during the study period
  • Chronic gastrointestinal disease: inflammatory bowel disease (Crohn's disease, ulcerative colitis), pancreatitis, short bowel syndrome
  • Gastrointestinal disease or disorders: inflammatory bowel disease (ulcerative colitis, Crohn's disease), irritable bowel syndrome, chronic diarrhea or constipation
  • Diagnosis of severe kidney disease (chronic kidney failure) or liver disease (hepatitis, cholestasis, liver failure)

Key Trial Info

Start Date :

August 15 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 10 2023

Estimated Enrollment :

277 Patients enrolled

Trial Details

Trial ID

NCT06193096

Start Date

August 15 2023

End Date

October 10 2023

Last Update

September 19 2024

Active Locations (1)

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Hospital de Cerdanya

Puigcerdà, Catalonia, Spain, 17520