Status:
UNKNOWN
Effects of Medical Treatment of ICAS With Hemodynamic Disorders Based on MR-FFR
Lead Sponsor:
Xuanwu Hospital, Beijing
Collaborating Sponsors:
National Key Research and Development Project, China
Conditions:
Stroke, Ischemic
Intracranial Atherosclerosis
Eligibility:
All Genders
30-80 years
Brief Summary
This multicenter prospective cohort study aims to compare the difference in the effects of medical treatment within 1 year between the two groups of ICAS patients divided hemodynamically by Magnetic R...
Eligibility Criteria
Inclusion
- Patients aged from 30 to 80 with symptomatic ICAS lesion in anterior circulation.
- 50% to 99% stenosis (in accordance with modified WASID method) confirmed by DSA, CTA or MRA.
- mRS 0-2 points
- Informed of the study protocol and objectives.
Exclusion
- Previous endovascular treatment or surgery for cerebrovascular diseases
- Large cerebral infarction (more than 1/2 MCA perfusion area) according to MRI
- Combined with other neurological diseases, such as aneurysm, arteriovenous malformation, tumor, hydrocephalus, cerebral trauma, cerebral hemorrhage, multiple sclerosis, epilepsy and intracranial infection.
- Pregnancy or in the preparation for pregnancy
- Patients who cannot tolerate or do not allow MR screening, including metal implanting and claustrophobia
- Contraindication for antiplatelet drugs or statins
- Patients with severe dementia or mental disorders, who cannot cooperate with examination
Key Trial Info
Start Date :
January 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT06196398
Start Date
January 1 2023
End Date
June 1 2024
Last Update
January 9 2024
Active Locations (1)
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1
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, China