Status:

UNKNOWN

Study on Exosome Changes in Patients With Proliferative Diabetic Retinopathy

Lead Sponsor:

Xuanwu Hospital, Beijing

Conditions:

Diabetic Retinopathy

Eligibility:

All Genders

18+ years

Brief Summary

Diabetic retinopathy is a common complication of diabetes and one of the leading causes of low vision and blindness in adults. In recent years, the prevalence of diabetes and the incidence of diabetic...

Detailed Description

一、Research Purpose 1. compared the changes of exosomes in intraocular fluid and blood of patients with proliferative diabetic retinopathy and non-diabetic patients. 2. analysed differentially express...

Eligibility Criteria

Inclusion

  • Age ≥18 years old;
  • Patients diagnosed with PDR by FFA and requiring vitrectomy for treatment;
  • Patients with no history of diabetes and diagnosed with macular anterior membrane or macular hiatus by color fundus photography and OCT;
  • Sign the informed consent form.

Exclusion

  • Suffering from cancer, immune diseases, infectious diseases and other systemic diseases;
  • Patients with retinal arteriovenous obstruction;
  • Intraocular infection;
  • Patients with uveitis;
  • In patients with high myopia, the equivalent spherical lens was \> -9.0D;
  • Recent history of cerebral infarction, myocardial infarction and other thrombus;
  • Patients with contraindications to surgery.

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06198543

Start Date

January 1 2024

End Date

April 1 2025

Last Update

January 10 2024

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Study on Exosome Changes in Patients With Proliferative Diabetic Retinopathy | DecenTrialz