Status:
RECRUITING
Safety and Efficacy of XJ-Procedure in Patients With Acute Type A Aortic Dissection Surgery
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Collaborating Sponsors:
Zhejiang Provincial People's Hospital
Second Affiliated Hospital of Nanchang University
Conditions:
Type A Aortic Dissection
Complication of Surgical Procedure
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This is a national, multicenter, open-label, randomized, controlled, endpoint-blinded clinical trial of patients diagnosed with ATAAD and undergoing "Sun's procedure" coordinated by the First Affiliat...
Detailed Description
In this study, the investigators will prospectively enroll patients diagnosed with ATAAD and undergo "Sun's procedure" from November 2024 to November 2027 in several centers, including the First Affil...
Eligibility Criteria
Inclusion
- Age 18-70 years;
- Patients with ATAAD attending the relevant department who have been assessed by a clinician as needing "Sun's procedure".
Exclusion
- Severe aortic root involvement (root diameter \>45 mm, root tear, severe destruction of the aortic root, combined valve disease);
- Combined coronary artery disease requiring concomitant coronary revascularization;
- Prior aortic or cardiac surgery;
- Preoperative severe malperfusion syndromes such as: severe cerebral complications (acute cerebral infarction, cerebral hemorrhage, coma, etc.); malperfusion of abdominal organs or lower extremities \>12 h;
- Preoperative combination of severe single or multiple organ failure;
- Pregnant women;
- Refused to sign the informed consent form and refused to participate in this study.
Key Trial Info
Start Date :
January 11 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
680 Patients enrolled
Trial Details
Trial ID
NCT06199401
Start Date
January 11 2024
End Date
December 1 2027
Last Update
July 12 2024
Active Locations (1)
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1
First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061