Status:
COMPLETED
Dual Ovarian Stimulation (Duostim) and Shanghai Protocols in Poor Ovarian Responders
Lead Sponsor:
Royan Institute
Conditions:
Assisted Reproductive Techniques
Eligibility:
FEMALE
35-45 years
Phase:
PHASE3
Brief Summary
A combination of follicular phase stimulation and luteal phase stimulation in the same cycle, can be a valuable choice in poor responder patients with reduced ovarian reserve, in order to achieve extr...
Detailed Description
The proposal of this randomized clinical trial study is a comparison of two different type of double stimulation protocols in patients who meet the POSEIDON (Patient-Oriented Strategies Encompassing I...
Eligibility Criteria
Inclusion
- Age ≥35 years
- Antimullerian hormone (AMH) \<1.2 ng/ml and/or Antral follicular count≤5 follicles
- ≤4 oocyte retrieved from previous ART cycle 4-18.5\<BMI\<30
Exclusion
- Endometriosis (stage III and IV)
- Myoma with a compression effect
- Uterine anomalies (Unicorn, Didelphis,etc,….)
- Male factor infertility with azoospermia, severe oligospermia and oligoasthenospermia, TESE/PESA
Key Trial Info
Start Date :
August 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 20 2023
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT06199960
Start Date
August 2 2019
End Date
November 20 2023
Last Update
January 10 2024
Active Locations (1)
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1
Royan Institute
Tehran, Iran