Status:

COMPLETED

Glucosamine Sulphate Versus Ginger in Non-Surgical Periodontal Therapy

Lead Sponsor:

Ain Shams University

Conditions:

Periodontal Pocket

Eligibility:

All Genders

25-50 years

Phase:

PHASE2

Brief Summary

Glucosamine (GlcN) is an N-deacetyl amino monosaccharide sugar derived from complete hydrolysis of chitosan in which it is important vector for chondroitin and keratin sulfate, while on the other hand...

Detailed Description

Periodontitis was described as a chronic multifactorial inflammatory disease associated with formation of plaque biofilms and characterized by progressive destruction of the tooth-supporting apparatus...

Eligibility Criteria

Inclusion

  • Localized periodontitis, probing depth ≥5 mm. Less than 30% of teeth are involved.
  • Age ranging from 25 to 50 years.
  • Good compliance with the plaque control instructions following initial therapy.
  • Availability for follow up and maintenance program.
  • Systemically free according to the American Society of Anesthesiologists (ASA I).

Exclusion

  • Smokers
  • Systemic diseases which could influence the outcome of the therapy (According to Cornell Medical Index-Health Questionnaire).
  • Pregnant and lactating females.
  • Vulnerable groups of patients' e.g. (prisoners, handicapped patients and decision ally impaired individuals).
  • Unwilling patients to perform oral hygiene measures of plaque control.
  • Patients with a history of allergy against any components of the two materials.
  • Previous Periodontal treatment or any use of antibiotic/anti-inflammatory drugs within the last 6 months before the initiation of the study

Key Trial Info

Start Date :

November 8 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 8 2023

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06200415

Start Date

November 8 2022

End Date

August 8 2023

Last Update

January 17 2024

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt