Status:

NOT_YET_RECRUITING

A Multi-center, Early Feasibility Study of Using the Mechanical Tissue Resuscitation™ (MTR™) Therapy System for Removal of Excess Fluid in Subjects Who Have Had a Portion of Their Skull Removed to Expose the Dura/Brain and Require Drainage for Fluid Removal.

Lead Sponsor:

Renovo Concepts, Inc.

Conditions:

Clinical Need for Craniotomy or Craniectomy

Eligibility:

All Genders

22-65 years

Phase:

NA

Brief Summary

A multi-center, early feasibility study of using the Mechanical Tissue Resuscitation™ (MTR™) therapy system for removal of excess fluid in subjects who have had a portion of their skull removed to exp...

Detailed Description

Mechanical Tissue Resuscitation (MTR™) is intended for short-term (up to 7 days) use to externally drain excess fluid volume from the site of surgery in patients who have undergone a surgical procedur...

Eligibility Criteria

Inclusion

  • Patient is willing and able to provide written informed consent.
  • The patient's age is ≥ 22 and ≤ 65 years.
  • The patient has a clinical need for a craniotomy/craniectomy and for which, as an integral part of their care, a Jackson Pratt (JP) drain would be placed at the surgical site.
  • The surgical case is classified as 'clean'.

Exclusion

  • Patient has suffered a traumatic brain injury.
  • Patient is pregnant or lactating.
  • Patient's BMI = (Weight (lb) x 703)/(〖Height〗\^2 (inches)) \> 45; BMI may also be calculated at http://nhlbi.nih.gov/health/educational/lose\_wt/BMI/bmicalc.htm
  • Patient is participating in another clinical investigation .
  • Patient's anticipated survival is \< 48 hours.
  • Patient is incarcerated at time of hospital admission.
  • Patient has a coincidental infection.
  • Patient has thrombocytopenia (platelet count \< 150,000/µL).
  • Patient has an International Normalized Ratio (INR) \> 1.5.
  • Patient is an active opioid abuser.
  • Patient is an active alcohol abuser.
  • There is active bleeding at the site of surgery.

Key Trial Info

Start Date :

January 15 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 15 2024

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT06201429

Start Date

January 15 2024

End Date

June 15 2024

Last Update

January 24 2024

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