Status:

TERMINATED

Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) Laser Treatment for Granular Corneal Dystrophy

Lead Sponsor:

Johns Hopkins University

Conditions:

Granular Dystrophy, Corneal

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Granular Corneal Dystrophy is a rare hereditary disease characterized by the development of deposits within the cornea, which may in turn affect the quality of vision. Still today, all existing treatm...

Detailed Description

Neodymium:yttrium aluminum garnet (Nd:YAG) laser is an ophthalmic instrument that finds versatile use in clinical practice since its first introduction in 1980s. This solid-state laser emits infrared ...

Eligibility Criteria

Inclusion

  • Patients older than 18 years of age
  • Diagnosis of granular corneal dystrophy with presence of granular opacities in the peripheral cornea of appropriate size (ca. 50 µm) in at least one eye
  • Willingness and ability to give signed informed consent and follow study instructions

Exclusion

  • Presence of any active intra-ocular inflammation
  • Pre-existing glaucoma or retinal edema
  • Cannot properly self-administer or receive an eye drop medication

Key Trial Info

Start Date :

January 26 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 9 2024

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT06202651

Start Date

January 26 2022

End Date

December 9 2024

Last Update

January 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Wilmer Eye Institute - Johns Hopkins Hospital

Baltimore, Maryland, United States, 21287