Status:
RECRUITING
The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder
Lead Sponsor:
Lithuanian University of Health Sciences
Conditions:
Major Depressive Disorder
Inflammation
Eligibility:
All Genders
18+ years
Brief Summary
Major depressive disorder (MDD) is a chronic mental illness, with 60% lifetime risk of recurrence after the first MDD episode. Despite available treatment options for MDD, only about half to two-third...
Eligibility Criteria
Inclusion
- ≥18 years old
- signed informed consent
- patients diagnosed with MDD (according to the WHO's \[2019\] International Classification of Diseases and related health problems categorization of mental disorders) for MDD group.
Exclusion
- diagnosis of other mental disorders during the past one-year period (for MDD group).
- diagnosis of any mental disorders within the past one-year period, previous suicide attempt, or current suicide risk identified in the study (for control group).
- diagnosis of somatic diseases that may affect changes in inflammatory factors in the body (for both groups)
Key Trial Info
Start Date :
June 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06203015
Start Date
June 1 2022
End Date
June 1 2024
Last Update
January 12 2024
Active Locations (2)
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1
Psychiatry Department, Hospital of Lithuanian University of Health Sciences Kaunas Clinics
Kaunas, Lithuania, 50161
2
Psychiatry Department, Hospital of Lithuanian University of Health Sciences Kaunas Clinics
Kaunas, Lithuania