Status:

RECRUITING

Monitoring of Patients With Diffuse Gliomas Using Circulating miRNAs

Lead Sponsor:

University Hospital, Caen

Conditions:

Glioma, Malignant

Eligibility:

All Genders

18+ years

Brief Summary

MicroRNAs are small non-coding RNAs involved in the post-transcriptional regulation of genes and, consequently, of intracellular signalling pathways that govern cellular behaviour (Komatsu et al., 202...

Detailed Description

Diffuse gliomas are the most common primary tumors of the central nervous system, representing around 3,400 cases per year in France (Defossez et al., 2019). Their grade varies from 2 to 4. Whatever t...

Eligibility Criteria

Inclusion

  • Major patient
  • Grade 4 diffuse glioma
  • Surgery in the neurosurgery department of Caen University Hospital
  • Patient affiliated to a social security scheme
  • Patient followed at Caen University Hospital
  • No opposition from patient

Exclusion

  • \- Patients who underwent biopsy (lack of material for study, limited interest of monitoring for these patients without surgical excision).
  • Patients with grade 1 circumscribed glioma or grade 2 or 3 diffuse glioma.
  • Other non-glial histologies, glioneuronal histology
  • Minor patients
  • Patient not affiliated to a social security scheme
  • A minor under guardianship or protection
  • Patient opposed to study

Key Trial Info

Start Date :

January 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06203496

Start Date

January 1 2024

End Date

December 31 2026

Last Update

January 12 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Arthur Leclerc

Caen, France, 14000