Status:

ENROLLING_BY_INVITATION

The Role and Mechanism of GPER-Hippo-CBS/H2S Pathway in Preeclampsia

Lead Sponsor:

Hao Feng

Conditions:

Preeclampsia

Eligibility:

FEMALE

Up to 40 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to learn about in health conditions. The main questions it aims to answer are: * The pathological significance of GPER in uterine artery dilation in preeclampsia * ...

Detailed Description

1. Measure the content of H2S in uterine arterial smooth muscle and circulation of normal pregnancy and PE pregnant women, and analyze the relationship between the content of H2S in uterine arterial s...

Eligibility Criteria

Inclusion

  • Full term pregnancy with clinical diagnosis of preeclampsia and normal pregnancy pregnant woman
  • Pregnant women undergoing lower segment cesarean section for delivery

Exclusion

  • Combined with chronic hypertension, kidney disease, intrahepatic cholestasis, etc Other basic diseases;
  • Multiple pregnancy
  • Pregnant women undergoing vaginal delivery
  • Normal pregnant women who are\<37 weeks or\>40 weeks pregnant

Key Trial Info

Start Date :

April 10 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2029

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT06205771

Start Date

April 10 2024

End Date

December 1 2029

Last Update

April 10 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The First Affiliated Hospital of Shandong First Medical University &Shandong Provincial Qianfoshan Hospital

Jinan, Please Select, China, 250000