Status:

NOT_YET_RECRUITING

Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Acute Respiratory Distress Syndrome

Delirium

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Early cognitive assessment of critically-ill acute respiratory distress syndrome (ARDS) patients with delirium using a multidimensional electrophysiological evaluation battery (mEEG) to identify and c...

Detailed Description

Delirium is an altered mental status associated with specific manifestations such as reduced ability to direct, focus, maintain and shift attention (DSM V criteria). The vulnerability of critically-il...

Eligibility Criteria

Inclusion

  • Patients admitted to the intensive care unit with ARDS (according to Berlin criteria)
  • Delirium (according to Confusion Assessment Method (CAM)-ICU criteria)
  • Membership of a social security scheme
  • Signed consent of the referring person
  • Discontinuation of any sedative agent for ≥ 72 hours

Exclusion

  • Pre-existing psychotic disorders
  • Pre-existing cognitive deficits (short Informant Questionnaire on Cognitive Decline in the Elderly (short IQCODE) ≥ 3,4)
  • Recent ICU admission (\> 5 days of ICU hospitalization within 6 months prior to current ICU admission)
  • Patients whose delirium cannot be reliably assessed due to blindness, deafness or inability to speak French
  • Patients whose life expectancy is unlikely to exceed 24 hours
  • Pregnant ans breastfeeding women
  • Patients under court protection
  • Patients who have already participated in the study

Key Trial Info

Start Date :

September 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06206473

Start Date

September 1 2024

End Date

December 1 2025

Last Update

July 5 2024

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