Status:
WITHDRAWN
Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery
Lead Sponsor:
Mayo Clinic
Conditions:
Skin Cancer
Skin Cancer Face
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to compare surgical site infection rates for patients treated with Mohs micrographic surgery after bilateral nasal swab with povidone iodine versus standard treatment incl...
Eligibility Criteria
Inclusion
- Non-pregnant, non-lactating/breastfeeding, non-incarcerated, English-speaking persons undergoing Mohs micrographic surgery (MMS) for malignant cutaneous neoplasms and receiving same-day defect repair by the MMS-performing surgeon
- Able to provide written informed consent prior to initiation of any study-specific procedures
- Able to swallow, retain, and absorb oral medications
- All malignant cutaneous neoplasms will be included
Exclusion
- On antibiotic treatment or established intolerance or contraindication to povidone-iodine
- Allergy to specific oral antibiotics that are utilized as part of the Mayo Clinic Antibiotic Prophylaxis protocol (cefalexin, azithromycin, clindamycin)
- Requiring oral antibiotic therapy for prophylaxis postoperative infectious endocarditis or hematogenous total joint infection
- Cases where skin reconstruction is performed with non-sterile gloves
- Patients with lesions on the legs, as dilute vinegar soaks are standard practice and this would be a confounder for preventing surgical site infection
- Patients at increased risk for severe infections, including patients on immunosuppressive medications and biologics, patients with a history of HIV infection, chronic lymphocytic leukemia, immunodeficiency syndromes, as well as patients with insulin-dependent diabetes mellitus
Key Trial Info
Start Date :
September 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2030
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT06207786
Start Date
September 1 2024
End Date
May 1 2030
Last Update
November 25 2024
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