Status:
RECRUITING
Perceptions of E-Cigarettes and Synthetic Cooling Agents, the ICE Study
Lead Sponsor:
Ohio State University Comprehensive Cancer Center
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Abuse Tobacco
Exposure
Eligibility:
All Genders
21-29 years
Phase:
NA
Brief Summary
This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.
Detailed Description
PRIMARY OBJECTIVES: I. Assess the abuse liability of e-liquids with and without the presence of synthetic cooling agents. II. Determine the impact of synthetic cooling agents and flavor on EC puffin...
Eligibility Criteria
Inclusion
- Aged 21-29 years
- Current exclusive e-cigarette (EC) user (defined as ≥ weekly use over the past 3 months)
- Willing to provide informed consent and abstain from using their EC at least 12 hours prior to the four lab sessions
- Read and speak English
Exclusion
- Recently COVID-19+ (defined as positive test in the past 30 days) or a recent COVID-19 hospitalization (defined as a hospitalization within the past 6 months)
- Unstable or significant psychiatric conditions (past and stable conditions will be allowed)
- History of cardiac event or distress within the past 3 months
- Are currently pregnant, planning to become pregnant, or breastfeeding (will be verified with urine pregnancy test)
- Have suffered from any serious lung disease or infection (e.g. , tuberculosis, cystic fibrosis, or lung cancer) in the past 30 days
- Have hemophilia or another type of bleeding disorder
- Are blind, severely visually impaired, deaf, hard of hearing, or have a severe motor disability
Key Trial Info
Start Date :
May 8 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2028
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06208202
Start Date
May 8 2024
End Date
June 1 2028
Last Update
February 20 2025
Active Locations (1)
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1
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210