Status:
RECRUITING
Modified Breath Test to Determine Anabolic Sensitivity Across Physical Activity States
Lead Sponsor:
University of Toronto
Conditions:
Resistance Exercise
Physical Inactivity
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
Developing tools to detect when our bodies are more resistant towards protein synthesis is valuable for identification of when someone may be at risk of losing body or muscle mass such as with aging o...
Detailed Description
Maintaining high-quality and abundant lean body mass (LBM) is crucial for growth, health, and performance across all ages, sexes, and activity levels. Body protein, including skeletal muscle, undergoe...
Eligibility Criteria
Inclusion
- Healthy young (age: 18-35 years)
- BMI between normal to overweight (18.5-29.9 kg/m2)
- if oral contraceptive (OC) user, must be on monophasic OCs for at least 3 months prior to study
- if non-OC user, then must have regular menstrual cycles (length: 25-35 days) for at least 3 months prior to study and at least 6 months off of OCs
Exclusion
- Chronic disease diagnosis (cardiovascular, thyroid, diabetes)
- Current or recent remission of cancer
- Regular use of NSAID (except low-dose aspirin), anticoagulants
- Use of prescription drugs that would impact muscle protein synthesis (e.g., Statins, Lithium, ADHD medication, etc..)
- Insertion of intrauterine device (IUD) - exception: copper
- Smoking
- Use of illicit drugs (growth hormones, testosterone)
Key Trial Info
Start Date :
January 15 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT06209424
Start Date
January 15 2024
End Date
April 30 2025
Last Update
January 17 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Goldring Centre for High Performance Sport at the University of Toronto
Toronto, Ontario, Canada, M5S2C9