Status:
NOT_YET_RECRUITING
Prolonged Anticoagulation Therapy on the Prognosis of Patients With Left Ventricular Thrombosis
Lead Sponsor:
Chinese Academy of Medical Sciences, Fuwai Hospital
Conditions:
Embolism and Thrombosis
Anticoagulation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A single-center, open-label, exploratory randomized controlled study is proposed with the following objectives: whether prolonging the duration of anticoagulation to 12 months, compared with 6 months ...
Eligibility Criteria
Inclusion
- ①Patients who have been clearly diagnosed with left ventricular thrombus by inpatient or outpatient cardiac ultrasound (including general ultrasound and acoustic imaging).
- ②Age \>= 18 years old
Exclusion
- Patients do not agree to participate in the study or have poor compliance in the past
- Contraindication to anticoagulation or allergy to anticoagulants ③Have received oral anticoagulation after diagnosis of left ventricular thrombus.
- Have undergone or are planning to undergo surgical procedures including left ventricular appendage thrombectomy, heart transplantation, ventricular wall tumor collapse, or valve replacement.
- Presence of other long-term indications for anticoagulation, such as mechanical valve implantation, atrial fibrillation, etc.
- Requirement for treatment with Tegretol and inability to change to clopidogrel bisulfate ⑦Presence of known malignant tumors, severe hepatic dysfunction (Child-Pugh classification B or less), severe renal dysfunction (creatinine clearance \<30ml/min), anemia (Hb \<100g/L), coagulation disorders and other underlying diseases, or life expectancy \<3 years ⑧ Female patients are pregnant or breastfeeding ⑨ Patients with antiphospholipid syndrome
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT06209892
Start Date
January 1 2024
End Date
December 1 2027
Last Update
January 18 2024
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