Status:

COMPLETED

35kDa Hyaluronan Fragment Treatment of Colorectal and Rectal Cancer

Lead Sponsor:

Nakhia Impex LLC

Conditions:

Cancer Pain

Eligibility:

All Genders

48-60 years

Phase:

NA

Brief Summary

HA35 (Bioactive HA or B-HA or HA35) have good tissue permeability (B-HA injection, Ministry of Health, Registration number L20200708MP07707). HA35 might not lose HA's bioactivities of binding to a var...

Detailed Description

The previous study has shown that naked mole rat who has high tissue content of hyaluronan and its fragments is insensitive to pain. The previous study has also shown that hyaluronan modulates pain-re...

Eligibility Criteria

Inclusion

  • All patients had different degrees of metastasis of the cancers, including bone metastasis.
  • All patients undergo targeted radiotherapy shortly before this study.
  • All the patient volunteers included in this study were allowed to use antibiotic compounds on and off during the treatment in order to prevent possible infection associated with the cancers for ethnic consideration.
  • The included patients were aged 48 to 60 years.

Exclusion

  • Can not independently determine the level of pain.
  • Severe bleeding and severe inflammation

Key Trial Info

Start Date :

December 20 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 5 2024

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06209970

Start Date

December 20 2023

End Date

March 5 2024

Last Update

April 17 2024

Active Locations (1)

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Qingdao Huinorde Science and Technology Co.,Ltd

Qingdao, Shandong, China