Status:
COMPLETED
Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
Lead Sponsor:
Ain Shams University
Conditions:
Propofol
Fentanyl
Eligibility:
All Genders
21-45 years
Phase:
NA
Brief Summary
The objective of this study is to evaluate the effect of adding dexmedetomidine on evoked potentials in adult patients undergoing spinal surgery under intravenous anesthesia
Detailed Description
A catastrophic complication of spinal surgery is nerve and spinal cord injury. The incidence of neurological defects after spinal surgery can be reduced from 3.7%-6.9% to less than 1% with proper elec...
Eligibility Criteria
Inclusion
- Age from 21-45 years.
- Both sexes.
- American Society of Anesthesiology (ASA) physical status II and III.
- Undergoing major spine surgery
Exclusion
- Refusal of procedure or participation in the study by patients.
- Patients with known history of allergy to one of study drugs
- Patients with nerve conduction pathway injury.
- Severe circulatory or respiratory disease.
- Cognitive or psychiatric illness that leads to inability to cooperate, speak or provide informed consent
- Patients with history of Myasthenia gravis, epilepsy , history of pacemaker implantation .
- Patients who need to be awakened during the procedure.
Key Trial Info
Start Date :
January 20 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2025
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT06210061
Start Date
January 20 2024
End Date
April 1 2025
Last Update
December 22 2025
Active Locations (1)
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1
Ain Shams University
Cairo, Egypt, 11591