Status:
UNKNOWN
Transcranial Alternating Current Stimulation in Patients With Disorders of Consciousness
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
Consciousness Disorders
Eligibility:
All Genders
14-80 years
Phase:
NA
Brief Summary
In recent years, many literatures have reported that tACS, as a non-invasive electrical brain stimulation technique, has been applied in depression, schizophrenia, dementia and other fields. The goal...
Detailed Description
Background: tACS is a transcranial nerve regulation technique ,it has been applied in depression, schizophrenia, dementia and other fields. However, the exact mechanism of tACS has not been fully eluc...
Eligibility Criteria
Inclusion
- 1\. Patients with consciousness disorders for more than 28 days following severe brain injury, assessed by the CRS-R scale to meet the criteria for VS or MCS; 2. Aged between 14 and 80 years; 3. Stable vital signs; 4. No neuromuscular function blockers and no sedation within the prior 24 hours;
Exclusion
- 1\. Locked-in syndrome; 2. Contraindications for EEG examination;HD-tACS stimulation. 3. Contraindications for MRI scanning, such as the presence of internal metallic implants; 4. Diseases and factors that may affect brain function assessment, such as metabolic disorders, poisoning, shock, etc.
Key Trial Info
Start Date :
December 5 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2024
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT06211439
Start Date
December 5 2022
End Date
October 31 2024
Last Update
January 18 2024
Active Locations (1)
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1
The First Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, China, 310000