Status:

NOT_YET_RECRUITING

Anti-infection Therapy Based on mNGS Etiological Diagnosis and Infection After Liver Transplantation

Lead Sponsor:

Shenzhen Third People's Hospital

Conditions:

Infection

Eligibility:

All Genders

18-65 years

Brief Summary

Liver transplantation is the most efficacious treatment for end-stage liver disease; however, postoperative infection remains a major complication and leading cause of recipient mortality. Specificall...

Detailed Description

Liver transplantation has been established as a highly effective treatment for end-stage liver disease, with continuous advancements in surgical techniques and immunosuppressive regimens significantly...

Eligibility Criteria

Inclusion

  • Recipient age \>18 years;
  • Clinical diagnosis of infection in the donor with administered anti-infective treatment;
  • Complete clinical data for both the donor and recipient.

Exclusion

  • Recipient age \<18 years;
  • Presence of surgery-related factors leading to death or infection, such as intraoperative cardiac arrest resulting in postoperative death, intraoperative bleeding exceeding 2000ml, postoperative complications like intestinal or bile leakage, graft dysfunction, or small liver syndrome;
  • Incomplete clinical data for the donor or recipient

Key Trial Info

Start Date :

February 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06212115

Start Date

February 1 2024

End Date

December 30 2027

Last Update

January 19 2024

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Shenzhen Third People's Hospital

Shenzhen, Shenzhen, China