Status:
RECRUITING
Dietary Fiber Before Colorectal Cancer Surgery
Lead Sponsor:
Wageningen University
Collaborating Sponsors:
Gelderse Vallei Hospital
VLAG Graduate School
Conditions:
Colorectal Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this randomized controlled trial is to investigate the feasibility of increasing preoperative dietary fiber intake in individuals with colorectal cancer who will undergo surgery. This will ...
Detailed Description
Rationale: Postoperative complications, affecting up to 50% of the patients with colorectal cancer (CRC) undergoing surgery, are associated with impaired quality of life and higher mortality rates. Th...
Eligibility Criteria
Inclusion
- Age ≥18 years;
- Being diagnosed with CRC and planned to undergo elective CRC resection;
Exclusion
- Previously have had a large abdominal resection, excluding appendectomy and cholecystectomy;
- Diagnosed with Crohn's disease, Ulcerative Colitis, Celiac Disease;
- Currently having a stoma;
- Known allergic reactions to plants from the Asteraceae (Compositae) family (e.g., lettuce, daisies, sunflowers, artichokes, sage, tarragon, chamomile, chicory etc.);
- Currently following a strict diet and unwilling or unable to change (e.g., gluten free or ketogenic diet);
- Currently using fiber supplements, prebiotics and/or probiotics and unwilling to stop using these for the duration of the intervention;
- Having a habitual dietary fiber intake \>30 g/day for women and \>40 g/day for men, measured with a food frequency questionnaire;
- Dementia or other cognitive disabilities that makes it impossible to fill out questionnaires correctly;
- Illiteracy (inability to read and understand Dutch).
Key Trial Info
Start Date :
April 29 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2026
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT06212817
Start Date
April 29 2024
End Date
May 1 2026
Last Update
November 18 2025
Active Locations (3)
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1
Rijnstate
Arnhem, Gelderland, Netherlands
2
Ziekenhuis Gelderse Vallei
Ede, Gelderland, Netherlands
3
Meander Medisch Centrum
Amersfoort, Utrecht, Netherlands