Status:
RECRUITING
Preliminary Clinical Study of NMN Intervention in Mild Ulcerative Colitis
Lead Sponsor:
The Third Xiangya Hospital of Central South University
Conditions:
Ulcerative Colitis Chronic Mild
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to compare the safety and efficacy of nicotinamide mononucleotide (NMN) and placebo in patients with mild ulcerative colitis (UC). The main question it aims to answe...
Eligibility Criteria
Inclusion
- Age ≥18 years old, ≤75 years old;
- Clinical diagnosis of mild active UC patients, the diagnosis standard reference inflammatory bowel disease diagnosis and treatment of the consensus of opinion 2018.
- Agreed to participate in this study, and sign the informed consent.
Exclusion
- Patients with ALT or AST more than 2 times the upper limit of normal, TBIL more than 2 times the upper limit of normal;
- The creatinine clearance patients less than 60 ml/min.
- The intestines or other parts have severely active infection patients need to use antibiotics or antiviral drugs;
- Crohn's disease and intestinal tuberculosis and other chronic intestinal infectious disease, intestinal malignant tumor patients;
- Pregnancy and lactation women;
- People with diabetes or screening period more than 7.0 tendency for fasting glucose/L or glycosylated hemoglobin exceed 6.5%;
- With serious mental illness, such as drugs and alcohol can't cooperate with the patients;
- Participated in any other clinical investigator within 1 month before the screening period;
- The researchers determine any other disease or condition is not suitable for patients participate in the study.
Key Trial Info
Start Date :
February 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 30 2025
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06214078
Start Date
February 1 2024
End Date
July 30 2025
Last Update
January 19 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China, 410013