Status:

NOT_YET_RECRUITING

Gastrointestinal Decompression in Stroke

Lead Sponsor:

Tianjin Medical University General Hospital

Conditions:

Stroke

Stomach Acidity

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Acute severe ischemic stroke is a life-threatening subtype of stroke. Due to stress ulcer and gastric reflux in acute stage, patients with severe ischemic stroke are always complicated with stomach bl...

Eligibility Criteria

Inclusion

  • Age 18-80 years
  • severe AIS, including NIHSS score\>20 in dominant hemisphere infarction, or NIHSS score\>15 in non-dominant hemisphere infarction, or NIHSS consciousness score \>1; · massive infarction, characterized by infarction area larger than 1/3 of the effected middle cerebral artery territory and/or the cerebellum territory presented in admitted computed tomography (CT) or MRI
  • onset-to-needle time within 24 hours
  • prestroke modified Ranking scales (mRS)≤1
  • sign the informed consent.

Exclusion

  • Recent respiratory infection and/or gastrointestinal bleeding
  • austere diseases such as tumors and dyscrasia
  • intention to undergo emergency thrombectomy
  • pregnant women or nursing mother
  • contraindication for gastric tubes
  • participating in other clinical trials within previous 3 months.

Key Trial Info

Start Date :

February 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06214091

Start Date

February 1 2024

End Date

July 1 2025

Last Update

January 22 2024

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