Status:
RECRUITING
Sex Effects on Blood Pressure With Handgrip Training
Lead Sponsor:
University of Massachusetts, Boston
Conditions:
Blood Pressure
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The goal of this intervention is to compare the blood pressure response of young females and males to a single bout of static handgrip exercise before and after static handgrip training (4 weeks). Th...
Detailed Description
Hypertension is still the leading modifiable risk factor for cardiovascular disease and a silent independent predictor of all-cause death worldwide. Projections for the US suggest that 41% of adults w...
Eligibility Criteria
Inclusion
- Ages between 18-40 years;
- Normal blood pressure as defined by the American Heart Association (\<130/90 mmHg);
- BMI \< 30 kg/m2;
- No cardiovascular risk factors and no clinically diagnosed cardiovascular disease;
- Being recreationally active (≤ 2 days of structured physical activity);
- Able to speak English.
Exclusion
- Diagnosed with cardiovascular disease (e.g., coronary artery disease, heart failure), musculoskeletal (i.e., osteoporosis and sarcopenia), metabolic disease (e.g., diabetes mellitus) and kidney disease;
- Taking antihypertensive or other vasoactive medications and cardioactive medication;
- Diagnosed with depression and/or anxiety disorders;
- Long COVID;
- Being a smoker;
- Being pregnant or having menstrual irregularities.
Key Trial Info
Start Date :
March 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06215014
Start Date
March 1 2024
End Date
October 1 2025
Last Update
May 13 2024
Active Locations (2)
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1
UMassachusetts Boston
Boston, Massachusetts, United States, 02125
2
University of Massachusetts Boston
Boston, Massachusetts, United States, 02125