Status:

RECRUITING

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

Lead Sponsor:

Novosibirsk Scientific Research Institute for Circulatory Pathology

Conditions:

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Eligibility:

All Genders

18-90 years

Brief Summary

Polymorphism in the GUCY1A3 gene worsens the activity of rCC, causing vasoconstriction and increased platelet aggregation. Studies have shown the association of the GUCY1A3 gene with the risk of coron...

Detailed Description

Acetylsalicylic acid is indicated for the prevention of cardiovascular complications after CABG. Class I. The level of evidence A. ECS recommendations, Russian recommendations of cardiologists. Howeve...

Eligibility Criteria

Inclusion

  • Stable ischemic disease 2- 4
  • CABG

Exclusion

  • the need to take any anticoagulants
  • thrombocytopenia
  • allergy to aspirin.

Key Trial Info

Start Date :

December 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2025

Estimated Enrollment :

800 Patients enrolled

Trial Details

Trial ID

NCT06215300

Start Date

December 1 2022

End Date

November 1 2025

Last Update

January 22 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Novosibirsk research institute of circulation pathology

Novosibirsk, Novosibirsk Oblast, Russia, 630055

2

Aleksey

Novosibirsk, Russia