Status:
RECRUITING
Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients
Lead Sponsor:
Guangdong Provincial People's Hospital
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients sch...
Detailed Description
Guangdong Provincial People's Hospital will be the lead center, with an additional 3 hospitals designated as satellite centers for the study. To sum up, these centers will recruit a total of 100 conse...
Eligibility Criteria
Inclusion
- Age\>18 years.
- Suspected or confirmed primary lung cancer with scheduled surgical treatment.
- Moderate-to-high perioperative risk, defined as FEV1\<60% of predicted value (wedge) or ppo FEV1\<60% of predicted value (lobectomy/segmentectomy) or VO2peak\<20 ml/kg/ min.
- Sign informed consent and accept to comply with the requirements of the study protocol.
- Completion of a baseline Complete cardiopulmonary exercise testing (CPET).
Exclusion
- Concurrent or previous history of other malignant tumors.
- Life expectancy less than 1 year.
- Dementia; infirmity; or inability to participate in sports (musculoskeletal limitations, namely, injuries, frailty, and weakness).
- Inability to maintain exercise training.
- Irregular vital signs (heart rate: \< 40 or \> 120 bpm at rest; blood pressure: systolic blood pressure \> 200 mm Hg or diastolic pressure \> 110 mm Hg; T: ≥ 38.5 or ≤ 36◦C; SpO2 ≤ 90%).
- Currently enrolling in any other clinical trials.
- Patient refusal.
Key Trial Info
Start Date :
January 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06215326
Start Date
January 23 2024
End Date
December 31 2026
Last Update
March 1 2024
Active Locations (1)
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1
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China, 510080