Status:
UNKNOWN
Multi-omics Analysis to Characterize the Invasive Evolution of Pulmonary Subsolid Nodules
Lead Sponsor:
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Conditions:
Adenocarcinoma of Lung
Eligibility:
All Genders
18+ years
Brief Summary
Current clinical follow-up frequency and treatment timing for pulmonary subsolid nodules (SSNs) rely mostly on whether the nodules grow, which may not accurately reflect the pathological status, and m...
Detailed Description
This prospective observational cohort study aims to recruit 120 patients with subsolid nodules (SSNs) and 100 healthy volunteers. Enroll 120 patients with SSNs planned for surgery and 100 healthy volu...
Eligibility Criteria
Inclusion
- Patients with SSNs
- Newly diagnosed patients with persistent SSNs confirmed by thin-section chest CT examination
- Patient areilling to undergo surgery
- Voluntarily sign a written informed consent form
- Healthy Volunteers
- Healthy volunteers aged 18-50 years, regardless of gender.
- No lung nodules detected on chest thin-section CT.
- No history of cancer.
- Voluntary sign a written informed consent form.
Exclusion
- Patients with SSNs
- Surgical contraindications
- Inability to cooperate with CT/MR examination to obtain high-quality images
- History of malignant tumors
- Previous targeted, immune, or ablation therapy
- Postoperative pathology of non-lung adenocarcinoma disease spectrum
- Other situations deemed unsuitable for participation in this study by the researchers
- Healthy Volunteers
- Drug abuse
- HIV infection or AIDS
- History of syphilis, gonorrhea, or other infectious diseases
- Hepatitis B or C virus carrier
Key Trial Info
Start Date :
January 22 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT06215885
Start Date
January 22 2024
End Date
December 1 2024
Last Update
September 24 2024
Active Locations (1)
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1
Cancer Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100021