Status:

RECRUITING

Quantitative Sensory Testing and Central Sensitization in Endometriosis

Lead Sponsor:

BC Women's Hospital & Health Centre

Collaborating Sponsors:

University of British Columbia

Conditions:

Endometriosis

Pain

Eligibility:

FEMALE

19-49 years

Brief Summary

Endometriosis is a gynecologic condition where there is growth of endometrial-like tissue outside the uterus, leading to severe pelvic pain. Despite conventional treatment, many patients experience pe...

Detailed Description

Purpose: To validate the Central Sensitization Inventory (CSI), the Pain Sensitivity Questionnaire (PSQ), the Douleur Neuropathique 4 (DN4) questionnaire, the painDETECT (PD-Q) questionnaire, the Self...

Eligibility Criteria

Inclusion

  • New or re-referral appointment at the BC Women's Centre for Pelvic Pain and Endometriosis.
  • Consented to be contacted for future research in the centre data registry (EPPIC NCT02911090; H16-00264).
  • Surgically confirmed endometriosis, current imaging diagnosis, or current clinically suspected endometriosis diagnosed at the new or re-referral appointment as coded in the registry.
  • 19 to 49 years old.
  • Willing and committed to completing six questionnaires about pain.
  • QST specific criteria
  • • Willing and committed to QST testing.

Exclusion

  • Currently pregnant or breastfeeding.
  • Post-menopausal.
  • Does not speak English - Patients who do not speak English will be excluded to maintain the safety and well-being of the patient, as not understanding the test and process may harm the patient and reduce the validity of the results. We do not have research funding for a translator. Additionally, patients who require a translator are not typically included in the data registry and therefore are unlikely to be in our sample.
  • QST specific criteria
  • Diabetes or neurological disease predisposing to neuropathic pain.
  • Previous laparotomy (i.e. large abdominal incision)
  • Physical trauma (ex., surgery, scaring) to heterotropic QST test site(s) (i.e. deltoid muscle in the shoulder, thenar eminence).

Key Trial Info

Start Date :

May 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06215937

Start Date

May 1 2024

End Date

January 31 2026

Last Update

August 7 2024

Active Locations (1)

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1

BC Women's Hospital + Health Centre

Vancouver, British Columbia, Canada, V6H 2N9