Status:
UNKNOWN
Corneal and Tear Film Changes in Chinese Patients With Type 2 Diabetes
Lead Sponsor:
He Eye Hospital
Conditions:
Dry Eye Disease
Tear Film
Eligibility:
All Genders
18-90 years
Brief Summary
Diabetes mellitus has been associated with ocular surface damage and exacerbates dry eye disease (DED) pathology. To investigate clinical and inflammatory changes in the ocular surface of insulin-inde...
Detailed Description
Diabetes mellitus (DM) is a developing global health challenge due to the multiple complications associated with long-term hyperglycemia. Although diabetic retinopathy is the most prevalent and well-k...
Eligibility Criteria
Inclusion
- Participants are diagnosed with dry eye according to the TFOS DEWS II diagnostic criteria: (a) OSDI questionnaire ≥13, (b) Non-invasive tear breakup time (NITBUT) \<10 s, (c) ocular surface staining \>5 corneal spots, greater than nine conjunctival spots (The presence of two or more criteria was used to establish a positive DE diagnosis).
- Age ≥ 18
Exclusion
- Active ocular infection, such as infectious, viral, chlamydial, or immunologic conjunctivitis
- A history of ocular surgery that might affect the corneal or tear film, such as corneal refractive surgery, keratoplasty, cataract surgery, or ocular laser surgery
- Long-term contact lens wear
- Other ocular diseases being treated might affect the corneal or tear film: such as glaucoma, dacryocystitis, uveitis, and pterygium.
Key Trial Info
Start Date :
December 30 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06218992
Start Date
December 30 2023
End Date
December 31 2024
Last Update
January 23 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
He Eye Hospital
Shenyang, Liaoning, China, 110034