Status:
RECRUITING
Effect of High Intensity Training on Motor and Cognitive Functions
Lead Sponsor:
Fondazione Don Carlo Gnocchi Onlus
Collaborating Sponsors:
Ente Ospedaliero Ospedali Galliera
Fondazione Italiana Sclerosi Multipla
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Fatigability is one of the most prevalent disorder in MS followed by walking, balance and cognitive disorders. However, there are few experimental studies on the effects of fatigability on balance an...
Eligibility Criteria
Inclusion
- More than 18 years of age
- Clinical diagnosis of Multiple Sclerosis (MS)
- Stable disease course without worsening more than 1 EDSS point over the last 3 months, -EDSS between 1.5 and 6 points
- Must be able to maintain upright posture without any assistance for 30 seconds
- Must be able to release a written informed consent.
Exclusion
- MS relapse within the previous three months;
- Unable to comprehend the aims of the study and to follow test instructions;
- Diagnosis of major depression (DSM-5);
- Severe joint and/or bone disorders interfering with balance and gait (based upon clinical judgment);
- Cardiovascular diseases;
- Unconfirmed or uncertain diagnosis of MS (McDonald criteria)
- Other concomitant neurological disease;
- Patients already performing aerobic or walking exercise.
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06219304
Start Date
September 1 2023
End Date
December 31 2025
Last Update
July 8 2025
Active Locations (1)
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1
Fondazione IRCCS Don Carlo Gnocchi
Milan, MI, Italy, 20148