Status:

RECRUITING

Neurorehabilitation Ecosystem for Sustained Therapy (NEST): A Feasibility Study

Lead Sponsor:

Hospital Universitari Vall d'Hebron Research Institute

Collaborating Sponsors:

Sint Maartenskliniek

NRCA - IRCCS Istituto Nazionale di Ricovero e Cura per Anziani

Conditions:

Stroke

Eligibility:

All Genders

18-80 years

Brief Summary

The global burden of stroke is staggering, with over 15M new cases reported annually. Of these cases, around 40% require motor and cognitive rehabilitation, resulting in approximately 6M new patients ...

Detailed Description

The main objective of the feasibility study is to assess 1) the usability, 2) adherence, 3) user experience and 4) acceptability of the NEST system during a six-week intervention. In particular, Inves...

Eligibility Criteria

Inclusion

  • Patients presenting a first-ever ischemic or hemorrhagic stroke at least three months prior to study recruitment, confirmed by brain CT or MRI;
  • Mild to moderate motor impairment of the upper extremity (MRC ≥ 2)
  • Age = 18 - 80 years old;
  • Able to sit in a regular chair or wheelchair;
  • Experience with smartphone technology

Exclusion

  • The presence of a condition or abnormality that could compromise the patient's safety or data quality;
  • Severe cognitive impairments that prevent the execution of the experiment (MoCA \< 19). This cut-off point is based on a pilot study (Maier, M. et al., 2019).
  • Arteriovenous malformation or other brain lesions not related to stroke;
  • Previous history of upper limb motor impairment
  • Sensory aphasia;
  • Associated impairments: spasticity of the upper limb (Modified Ashworth scale≥ 3), apraxia, major pain, or other impairments that would interfere with the correct execution of the experiment;
  • The NEST system cannot be used independently according to the therapist's observations and there is no available support from a caregiver to help use the system;
  • No experience with smartphone technology.

Key Trial Info

Start Date :

January 15 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 30 2024

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT06219382

Start Date

January 15 2023

End Date

April 30 2024

Last Update

January 23 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

INRCA

Ancona, Italy

2

Sint Maartenskliniek

Nijmegen, Netherlands

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