Status:
RECRUITING
Reinnervation and Neuromuscular Transmission in ALS
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
Aarhus University Hospital
Conditions:
Amyotrophic Lateral Sclerosis
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to describe the changes in the neuromuscular connection in patients with amyotrophic lateral sclerosis (ALS). The study consist of three substudies that have the following mai...
Eligibility Criteria
Inclusion
- Referred to clinical neurophysiological examination on suspicion of motor neuron disease or diagnosed with ALS according to Gold Coast criteria within the last 3 months.
- Age ≥18 years old
- Able and willing to provide informed consent
Exclusion
- Former central or peripheral nervous system disease
- Diabetes
- Electrophysiological signs of polyneuropathy at baseline visit
- Pacemaker
- Pregnancy
- For disease controls the exclusion criteria are the same, but the inclusion criteria:
- Diagnosed with disease with slow, progressive loss of motor neurons
- Age ≥18 years old
- Able and willing to provide informed consent
Key Trial Info
Start Date :
May 17 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06219759
Start Date
May 17 2024
End Date
December 1 2026
Last Update
August 7 2024
Active Locations (1)
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1
Department of Neurology, Aarhus University Hospital
Aarhus, Central Jutland, Denmark, 8200