Status:

NOT_YET_RECRUITING

Testing the Safety and Efficacy of a Novel Barrier Cream for the Treatment of Moisture Associated Skin Damage

Lead Sponsor:

Scotiaderm

Collaborating Sponsors:

The Salvation Army Toronto Grace Health Centre

Conditions:

Moisture Associated Skin Damage

Incontinence Associated Dermatitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Liquid stool and diarrhea are associated with an increased risk for moisture-associated skin damage (MASD), and clinical evidence suggests that exposure to liquid stool is associated with severe MASD ...

Detailed Description

Moisture associated skin damage (MASD) is a grouping of painful, irritating rashes which occur when a patient has repeated or prolonged exposure to moisture from perspiration, urine and/or feces. Comm...

Eligibility Criteria

Inclusion

  • Patients who meet all the below criteria will be eligible for inclusion in the study:
  • ≥18 years of age;
  • Clinical diagnosis of incontinence-associated dermatitis resulting from diarrhea and/or fecal incontinence;
  • Minimum expected stay in hospital of two weeks;
  • Able to provide written informed consent (OR consent by a recognized substitute-decision maker) including explicit consent to take daily photographs of the rash associated with MASD.
  • Patients who meet any of the following exclusion criteria will not be eligible for enrolment:
  • History of complex skin disorders (such as psoriasis or eczema);
  • Allergy to any of the ingredients in the study product;
  • Visual evidence of a bacterial skin infection;
  • Anticipated length of stay in hospital less than two weeks;
  • Life expectancy less than two weeks;
  • Use of a dressing or bandage covering the rash that cannot reasonably be removed for required study activities without compromising patient comfort or care.
  • Note: Patients who are pregnant will not be excluded from the study unless they present with a rash or other skin conditions that may confound assessments.

Exclusion

    Key Trial Info

    Start Date :

    August 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 1 2026

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT06221046

    Start Date

    August 1 2025

    End Date

    November 1 2026

    Last Update

    May 15 2025

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    Testing the Safety and Efficacy of a Novel Barrier Cream for the Treatment of Moisture Associated Skin Damage | DecenTrialz