Status:

RECRUITING

PPG vs. ICG in Gastrointestinal Resections

Lead Sponsor:

Saint Petersburg State University, Russia

Collaborating Sponsors:

Shandong Linglong Yingcheng Hospital

High-Tech Clinic Beloostrov

Conditions:

Anastomosis

Perfusion

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This randomized controlled trial compares a novel optical technique against the standard of care for assessing tissue perfusion in gastrointestinal surgery. Participants are randomized to receive eith...

Detailed Description

This randomized, parallel-group clinical study aims to compare two intraoperative imaging strategies for assessing tissue perfusion in a spectrum of gastrointestinal anastomoses, including both gastro...

Eligibility Criteria

Inclusion

  • Adult patients (age ≥ 18 years).
  • Scheduled to undergo an elective gastrointestinal resection requiring a primary gastro-intestinal or entero-enteric anastomosis.
  • Able to understand and provide written informed consent.

Exclusion

  • Known hypersensitivity or allergy to indocyanine green (ICG), iodine, or any component of the ICG formulation.
  • Severe hepatic impairment (e.g., Child-Pugh Class C).
  • Pregnancy or lactation.
  • Emergency surgery.
  • Inability to comply with the study protocol or follow-up schedule in the investigator's judgment.

Key Trial Info

Start Date :

November 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2026

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06222645

Start Date

November 1 2023

End Date

May 31 2026

Last Update

November 18 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Shandong Linglong Yingcheng Hospital

Yantai, Shandong, China, 265400

2

High-Tech Clinic Beloostrov

Saint Petersburg, Leningradskaya Oblast', Russia, 197729

3

Department of Faculty Surgery, Saint Petersburg State University

Saint Petersburg, Leningradskaya Oblast', Russia, 199034