Status:

RECRUITING

Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine

Lead Sponsor:

AbbVie

Conditions:

Migraine

Eligibility:

All Genders

18-75 years

Phase:

PHASE3

Brief Summary

A migraine attack is a moderate or severe headache that usually occurs on one side of the head and is often accompanied by throbbing, sensitivity to light, sensitivity to sound, nausea, or other sympt...

Eligibility Criteria

Inclusion Criteria:

  • History of migraine (with or without aura) according to the International Classification of Headache Disorders 3rd Edition (ICHD-3) for >= 12 months prior to Visit 1/Screening.
  • History of 2 to 8 migraine attacks of moderate to severe headache pain in each of the 3 months prior to Visit 1/Screening per investigator judgment.
  • Migraine onset before the age of 50.
  • History of migraines lasting between 4 and 72 hours when untreated or treated unsuccessfully and migraine episodes separated by at least 48 hours of headache pain freedom.

Exclusion Criteria:

  • History of an average of 15 or more headache days per month in the 6 months prior to Visit 1/Screening per the investigator's judgment, or a current diagnosis of chronic migraine as defined by ICHD-3.
  • Require hospital/emergency room treatment for migraine attacks on 3 or more occasions within 6 months prior to Visit 1/Screening.

Key Trial Info

Start Date :

March 25 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2026

Estimated Enrollment :

1300 Patients enrolled

Trial Details

Trial ID

NCT06241313

Start Date

March 25 2024

End Date

November 1 2026

Last Update

April 14 2026

Active Locations (149)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 38 (149 locations)

1

Universitair Ziekenhuis Antwerpen /ID# 257582

Edegem, Antwerpen, Belgium, 2650

2

Universitair Ziekenhuis Brussel /ID# 257584

Jette, Brussels Capital, Belgium, 1090

3

Cabinet Prive Dr Sava /ID# 257581

Saint-Nicolas, Liege, Belgium, 4420

4

Jessa Ziekenhuis /ID# 257578

Hasselt, Limburg, Belgium, 3500