Status:
RECRUITING
A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation
Lead Sponsor:
Takeda
Conditions:
Cytomegalovirus (CMV)
Kidney Disease
Eligibility:
All Genders
18+ years
Brief Summary
The main aim of this study is to assess the safety of maribavir in adults with severe CKD or comorbid ESRD including participants on artificial filtering of the kidney (dialysis) or the blood (hemodia...
Eligibility Criteria
Inclusion
- Adults more than and equal to (≥) 18 years of age at index date.
- Diagnosis of comorbid ESRD or comorbid severe CKD prior to the index date.
- If ESRD (including participants on peritoneal dialysis or hemodialysis): participant diagnosed with ESRD confirmed by an estimated glomerular filtration rate (eGFR) less than (\<) 15 milliliters per minute per 1.73 square meters (mL/min/1.73m\^2).
- If severe CKD: participant diagnosed with severe CKD confirmed by an eGFR of 15 to \<30 mL/min/1.73m\^2 at index.
- Participant has undergone solid organ transplant (SOT) or hematopoietic stem cell transplantation (HSCT) before index date.
- Participant was diagnosed with refractory (with or without resistance) CMV during the latest post-transplant period.
- Participant initiated treatment with maribavir in routine practice within the eligibility period and received at least 1 dose of maribavir.
- Informed consent provided (where required by local regulations) before data collection commences.
Exclusion
- There are no exclusion criteria for this study.
Key Trial Info
Start Date :
November 3 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2027
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06243731
Start Date
November 3 2025
End Date
January 31 2027
Last Update
December 16 2025
Active Locations (25)
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1
Hopital Erasme - PPDS
Anderlecht, Brussels Capital, Belgium, 1070
2
UZ Leuven - PPDS
Leuven, Vlaams Brabant, Belgium, 3000
3
North Estonia Medical Centre Foundation
Tallinn, Harju, Estonia, 13419
4
Tartu University Hospital
Tartu, Estonia, 60535