Status:

RECRUITING

First Observatory of Precocious Puberty.

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Puberty, Precocious

Eligibility:

All Genders

Up to 11 years

Brief Summary

The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study p...

Eligibility Criteria

Inclusion

  • Precocious puberty group (PP) :
  • Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear)
  • Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear)
  • Advanced puberty group (AP) :
  • Suspected advanced puberty (girl aged ≥ 8 and \< 10 years or boy aged ≥ 9 and \< 11 years when the first signs of development\* appear)
  • First consultation with the investigator (pediatric endocrinologist).
  • Control group :
  • Boy or girl without signs of pubertal development (Tanner 1);
  • Matched to the PP group on sex and age (+/- 1 year);
  • Consultation with the same investigator over the same period (same quarter) as a patient in the PP group

Exclusion

  • All groups
  • Consultation with the same investigator over the same period (same quarter) as a patient in the PP group
  • Family not speaking French, language barrier.

Key Trial Info

Start Date :

June 26 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 26 2028

Estimated Enrollment :

3360 Patients enrolled

Trial Details

Trial ID

NCT06263868

Start Date

June 26 2024

End Date

June 26 2028

Last Update

January 16 2026

Active Locations (25)

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Page 1 of 7 (25 locations)

1

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France, 69130

2

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France, 69130

3

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France, 69130

4

Pediatric practice

Lyon, Auvergne-Rhône-Alpes, France, 69006