Status:
RECRUITING
A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis
Lead Sponsor:
Nanfang Hospital, Southern Medical University
Conditions:
Radiation-induced Oropharyngeal Mucositis
Swallowing-induced Breakthrough Pain
Eligibility:
All Genders
18+ years
Brief Summary
The performance of the predictive models for severe oropharyngeal mucositis established using current oral mucosal contouring method was unsatisfactory in nasopharyngeal carcinoma (NPC). Whereas the p...
Detailed Description
Nasopharyngeal carcinoma (NPC) is particularly prevalent in southern China. Radiation-induced oropharyngeal mucositis is one of the most common acute toxicities in patients with NPC receiving radiothe...
Eligibility Criteria
Inclusion Criteria:
- Provide informed written consent.
- Age ≥ 18 years.
- Histologically confirmed as nasopharyngeal carcinoma, and currently undergoing radical radiotherapy or chemoradiotherapy.
- Complete and continuous records of oral / oropharyngeal mucositis grading, and self-reported swallowing-induced breakthrough pain.
Exclusion Criteria:
- Existence of poor oral hygiene, untreated dental or periodontal diseases, and metal dental restorations.
- Current untreated or unresolved conditions like unstable heart diseases requiring treatment, and poorly controlled diabetes mellitus.
- Body mass index (BMI) <18.5.
- Unsuitable to participate in current study, according to researchers' assessment.
Key Trial Info
Start Date :
March 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT06287788
Start Date
March 1 2024
End Date
December 31 2026
Last Update
March 1 2024
Active Locations (1)
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1
Southern Medical University
Guangzhou, Guangdong, China, 510515