Status:
RECRUITING
A Home-based Exercise and Physical Activity Intervention After Liver Transplantation: Impact of Exercise Intensity
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Collaborating Sponsors:
KU Leuven
Conditions:
Liver Transplantation
Physical Fitness
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Research demonstrated that transplant recipients benefit from physical activity, but there is a gap in knowledge regarding the required intensity. In the PHOENIX-Liver study, researchers aim to invest...
Detailed Description
Liver transplantation constitutes the only curative treatment for patients with end-stage liver disease. Advances in the field have led to favourable short- and medium term (1-3 year) post-transplant ...
Eligibility Criteria
Inclusion Criteria:
- de novo adult liver transplant recipients with a transplant vintage of two to three months
- access to a home freezer (± -18°C)
Exclusion Criteria:
- Aberrant CPET (abnormal low cardiorespiratory fitness is not considered an exclusion criteria), unstable angina, life-threatening arrhythmias, uncontrolled hypertension/diabetes, HbA1c ≥ 9%, severe pulmonary disease (FEV1 < 50%), musculoskeletal disorders not allowing physical training on a cycle ergometer, or any other medical reasons by the physician considered to be a contraindication for moderate or high-intensity physical exercise
- multi-organ transplantation (exception: combined liver-kidney transplant is considered eligible for participation)
- ongoing treatment for malignancies
- unable to understand Dutch
- no access to smartphone and/or computer with internet access
- does not willing to except the general conditions of Coachbox. Preparticipation medical screening (cardiopulmonary exercise testing with 12-lead ECG + stratification of cardiovascular risk factors) will be performed by a cardiologist (Dr. Kaatje Goetschalckx at UZ Leuven).
Key Trial Info
Start Date :
March 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
147 Patients enrolled
Trial Details
Trial ID
NCT06302205
Start Date
March 1 2023
End Date
December 1 2026
Last Update
April 1 2024
Active Locations (1)
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1
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000